Hand, Foot, and Mouth Disease

Dr. Lara Varisco Leonhardt, MD

What is hand, foot, and mouth disease?

Hand, foot, and mouth disease is a disease caused by a virus. The disease causes sores in the mouth as well as blisters on the hands and feet. It mainly occurs in children age 6 months to 4 years.

Symptoms can include:

  • small, painful ulcers in the mouth
  • small water blisters or red spots located on the palms of the hands, soles of the feet, and on the webs between the fingers and toes
  • 5 or fewer blisters per hand or foot
  • sometimes, small blisters or red spots on the buttocks
  • a fever between 100°F and 102°F (37.8°C and 38.9°C).

What is the cause?

Hand, foot, and mouth disease is caused by the Coxsackie A-16 virus. It has no relationship to hoof and mouth disease of cattle. Outbreaks occur most often in the summer and fall.

How long does it last?

The fever and discomfort are usually gone in 3 or 4 days. The mouth ulcers will heal in about 7 days, but the rash on the hands and feet can last 10 days. The only complication seen with any frequency is dehydration from children refusing to drink fluids.

How can I take care of my child?

  • Antacid solution for pain relief

For young children over 1 year old, put 1/2 teaspoon antacid solution, Maalox, and half teaspoon Benadryl  in the front of the mouth three times a day after meals. Children over age 4 can use 1 teaspoon of an antacid solution as a mouthwash after meals.

  • Diet

Offer a soft diet. Use a cup instead of a bottle to give fluids to very young children. Cold drinks, milkshakes, Popsicles, and sherbet are good choices. Avoid citrus, salty, or spicy foods.

  • Medication

Give acetaminophen or ibuprofen for severe mouth pain or fever over 102°F (38.9°C).

  • Contagiousness

Hand, foot, and mouth disease is quite contagious. Usually some of your child's playmates will develop it at about the same time. The incubation period after contact is 3 to 6 days. Because the spread of infection is extremely difficult to prevent and the condition is harmless, these children do not need to be isolated. They can return to day care or school when the fever returns to normal. While most children are contagious from 2 days before to 2 days after the rash, avoiding other children is unnecessary.

When should I call my child's healthcare provider?


  • Your child has not urinated for more than 8 hours.
  • Your child develops a stiff neck.
  • Your child starts acting very sick.

Call during office hours if:

  • The fever lasts more than 3 days.
  • You have other concerns or questions.

Pediatric services are available to all children; office visit fees can be billed to medical insurance or paid in cash.
A sliding schedule of fees for uninsured children is available. Contact us now for more information.
The information contained in this website is to provide information of a general nature about the
practice and pediatric medical conditions. Neither Dr. Leonhardt nor Bee Well Pediatrics, P.A. is engaged in rendering medical
advice or recommendations. You should always consult your doctor for advice.